Request KCGS

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The first release of KCGS is available for distribution. The fee for KCGS v1.0 is $3,100, which helps to defray resynthesis costs to make KCGS a sustainable resource for all research labs. KCGS is supplied in 1µL aliquots of a 10 mM stock solution in DMSO of 188 compounds. You will have access to the chemical structure and to kinome-wide selectivity data for each compound, and you can receive 5µL of up to 5 compounds for follow-up screening. For additional cherry picks, cost is determined by quantity requested.

The Structural Genomics Consortium (SGC) accelerates research in new areas of human biology and drug discovery
(1) by ensuring that its Materials and research outputs derived from them are available in the public domain to the scientific community on a pre-competitive basis, without restrictions based on patents or other forms of intellectual property, and (2) by creating an open collaborative network of scientists around the world who are committed to this principle.

The Material is therefore entrusted to you for the benefit of
(1) the SGC and its members (including your Establishment where applicable),
(2) individual members of the scientific research community whose work may be advanced by open access to the Material and to research results and data outputs arising from your use of the Material, and
(3) individual members of the general public whose health may be ameliorated or improved as a result of your work with the Material, and the work of other members of the scientific community who enjoy free and open access to the Material (together, the “Beneficiaries”).

Your obligations as trustee as described to the right do not extend to new compounds that may be generated or synthesized in connection with your use of the Material (the ‘Modifications’). Modifications mean changes to the chemical structure of the Material, including rearrangements of covalent bonds or additions or removals of atoms, residues, or moieties connected by covalent bonds, except ester forms. Modifications do not include resolved stereoisomers, salt forms, hydrates, solvates, polymorphs, complexes, or other non- covalent derivatives of the Material, nor do they include methods of synthesis, uses, formulations, or dosages of the Material.

This is a 3 step process:

Step 1: Fill out the KCGS web form below
Step 2: Download the MTA file (that will appear after the web form is completed) and have it signed by an authorized institutional signator.
Step 3: Log into infoporte to upload the signed MTA and pay for your order by credit card. Once the MTA has been approved, a payment link will be emailed to you. After payment has been received, your compounds will be shipped to the address provided. Please refer any questions to sgc-unc@unc.edu.

Name *
Name
This address must be able to accept shipments on dry ice
Please describe the research that will be enabled by this set
By accepting the Material, you agree to hold the Material in trust for the benefit of the Beneficiaries, and, in your capacity as a trustee, you agree to the following obligations and responsibilities with respect to the Material: *
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